Our results indicate Qu/Lys-CNGs could be an effective bifunctional agent for clinical applications to treat bacterial ocular diseases.

He believed that some individuals are predisposed to experience life more intensely and this predisposes them to frequent and severe crisis. Furthermore, the Qu/Lys-CNGs can penetrate into the cornea via epithelial tight junction opening, thereby exerting superior antibacterial and antioxidant therapeutic effects against S. Dbrowski called his work the Theory of Positive Disintegration to reflect the central and positive role disintegration plays in development. In vitro cytotoxicity and hemolysis assays and in vivo corneal biocompatibility evaluations revealed good biocompatibility of Qu/Lys-CNGs as a safe nanomedicine in ophthalmic drop formulation. Disintegration of peripheral structures of the bacteria caused by Qu/Lys-CNGs is due to their strong and specific interaction with bacterial membranes. The Qu/Lys-CNGs display broad-spectrum bacteriostatic effects against non-multidrug-resistant bacteria, Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Salmonella enteritidis, and also against multidrug-resistant bacteria, methicillin-resistant Staphylococcus aureus. These Qu/Lys-CNGs synthesized by dry heating inherit and amplify the advantages of two natural products, including excellent antioxidant capacity and high positive charge. Writer and academic Dr Richard Barbrook will give a short introduction to Warks work and to Situationism and its relevance to.

Here, we have developed a one-step method to synthesize carbonized nanogels (CNGs) from biogenic quercetin (Qu) and lysine (Lys) as a bifunctional agent with antibacterial and antioxidant properties for topical BK therapy. McKenzie Wark, author of The Beach Beneath the Street, will give a talk at Furtherfield Gallery (London) about his latest book The Spectacle of Disintegration - Situationist Passages Out of the 20th Century. Positive disintegration is often correlated with a higher degree of over-excitability, which is another way to say that people who develop themselves thoroughly often feel they are in a state of. To prevent visual loss, clinical therapy of severe bacterial keratitis (BK) demands simultaneous remedying of the damage caused by bacterial infection and its induced oxidative stress/inflammation of the cornea. Carbonized nanogels for simultaneous antibacterial and antioxidant treatment of bacterial keratitis